my hubby and friends used to play risk on a regular basis, leaving games set up for as long as it took... but that was before kids (but still, they aren't that bad, mission)
I liked Pictionary, because I can draw adequately, and lately I've been liking hearts. even my kids can play that, well, not my 4yo, but she thinks she can... she can play dominos, tho :)
we all enjoy uno a lot too!